relation between third trimester urinary iodine concentrations and newborn thyrotrophic hormone

نویسندگان

mohammad reza rezvanfar department of internal medicine, faculty of medicine, arak university of medical sciences, arak, iran

heidar farahani department of biochemistry, faculty of medicine, arak university of medical sciences, arak, iran

mohammad rafiei 3 department of biostatistics, faculty of medicine, arak university of medical sciences, arak, iran

elaheh salehi arak university of medical sciences, arak, iran

چکیده

background: the aim of the study was to evaluate the third trimester urinary iodine excretion and to assess its relation with newborns thyroid function. materials and methods: a total  of  208 healthy third trimester pregnant women without previous history of thyroid disease were included in the study. urinary iodine levels of mothers were measured and neonatal tsh levels were screened on the 3- 5th day following birth.  results: the median urinary iodine level in the mothers was 50μg/l. according to who criteria for iodine status:14.9%, 34.1% and  49.6%  had severe, moderate and  mild iodine deficiency, respectively, and only 1.4%, had  the adequate iodine intake . in 6 neonate (2.8%) who their tsh level were between 5- 10 iu/ml, nobody had criteria for congenital hypothyroidism at recall visit (15th day). our results showed the reverse relation between mean neonatal tsh levels and mother’s third trimester iodine level (r= -0.19, p=0.006). conclusion: although all of  mothers included in this study stated that they were using iodized salt, iodine deficiency was frequent . there was also a significant relation between mean neonatal tsh levels and mother’s third trimester iodine urinary level.

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عنوان ژورنال:
archives of medical laboratory sciences

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